Susceptibility Gene Prediction in Hereditary Disease Retinoblastoma
نویسندگان
چکیده
منابع مشابه
Thermochemotherapy in hereditary retinoblastoma.
BACKGROUND/AIM The combination of chemotherapy and transpupillary thermotherapy, thermochemotherapy (TCT) has become an established part of the treatment plan in advanced retinoblastoma. The aim of this study was to identify safe indications, the complications as well as the limitations of this new treatment for retinoblastoma. METHODS Tumour response and side effects of TCT with an indirect ...
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Retinoblastoma is a rare type of eye cancer that usually occurs in early childhood, usually before the age of five. This type of cancer occurs in the retina, the light-sensitive tissue behind the eye that recognizes light and color. It is the most common type of eye cancer in children. One-third of all retinoblastomas are inherited, meaning that mutations in the RB1 gene are present in all cell...
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The hereditary form of retinoblastoma (Rb) is associated with a germ line mutation in one RB allele and is characterized by the occurrence of multiple, bilateral Rb tumors and a predisposition to the development of second cancers. In an earlier study, we observed an unexpected hypersensitivity to ionizing radiation in skin fibroblasts derived from unaffected parents of children with hereditary ...
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The hereditary form of retinoblastoma (Rb) is associated with a germ line mutation in one RB allele and is characterized by the occurrence of multiple, bilateral Rb tumors and a predisposition to the development of second cancers. In an earlier study, we observed an unexpected hypersensitivity to ionizing radiation in skin fibroblasts derived from unaffected parents of children with hereditary ...
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One of the main problems in genetic epidemiology is to robustly predict genetic susceptibility to complex diseases based on the data from case/control studies. This becomes computationally challenging in presence of interactions between multiple genes. In order to efficiently search through enormous amount of possible combinations, it is necessary to apply heuristics and the greedy approach has...
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ژورنال
عنوان ژورنال: International Journal of Advanced Engineering Research and Science
سال: 2017
ISSN: 2349-6495,2456-1908
DOI: 10.22161/ijaers.4.4.38